Advanced applications of DNA nanostructures dominated by DNA origami in antitumor drug delivery

DNA origami is a cutting-edge self-assembly technique that neatly folds strands and creates specific structures based on the complementary base pairing principle. These innovative nanostructures provide numerous benefits, including lower biotoxicity, increased stability, superior adaptability, making them an excellent choice for transporting anti-tumor agents. Furthermore, they can considerably reduce side effects improve therapy success by offering precise, targeted, multifunctional drug delivery system. This comprehensive review looks into principles design strategies of origami, providing valuable insights this technology’s latest research achievements development trends in field delivery. Additionally, we key function major benefits cancer treatment, some these approaches also involve aspects related to tetrahedra, aiming novel ideas effective solutions address challenges therapy.